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pentobarbital will lessen the level or effect of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital will lower the level or result of carvedilol by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.Breastfeeding considerations: In breastfeeding considerations, it should